Year: [2016] [2015] [2014] [2013] [2012]  
2016 top
1 He X, Tan C, Wang F, Wang Y, Zhou R, Cui D, You W, Zhao H, Ren J and Feng B (2016). Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair. Nucleic Acids Research. [PMID: 26850641; Epub ahead of print]. [Abstract]
2 Lee PSC, Zhang LML, Lu AY, Lam KYC, Dong TTX, Lin H, Chan GKL and Tsim KWK (2016). Indication of Nerve Growth Factor Binding Components from Herbal Extract by HerboChip®: A Novel Platform for Drug Screening on a Chip. Chinese Medicine. (In Press).
3 Li S, Yang C, Zhang L, Gao X, Wang X, Liu W, Wang Y, Jiang S, Wong YH, Zhang Y and Liu K (2016). Promoting axon regeneration in the adult CNS by modulation of the melanopsin / GPCR signaling. Proceedings of the National Academy of Sciences. 113(7):1937-1942. [Abstract]
4 Ma HT and Poon RYC (2016). TRIP13 regulates both the activation and inactivation of the spindle-assembly checkpoint. Cell Reports. 14:1086-99. [Abstract]
5 Zhang J, Guo S, Chan KW, Tong EPS, Fu GM, Mu Q, Ip FCF and Ip NY (2016). New lignans with neuroprotective activity from Adelostemma gracillimum . Phytochemistry Letters. 16:1-7.
2015 top
1 Cao S, Sheong FK and Huang X (2015). Reference interaction site model with hydrophobicity induced density Inhomogeneity: An analytical theory to compute solvation properties of large hydrophobic solutes in the mixture of polyatomic solvent molecules. The Journal of Chemical Physics. 143(5):054110,1-10. [Abstract]
2 Chen Y, Liang Z, Fei E, Zhou X, Fang W, Fu WY, Fu AK and Ip NY (2015). Axin regulates dendritic spine morphogenesis through Cdc42-dependent signaling. PLoS One. 10:e0133115, 1-12. [Abstract]
3 Du K, Zheng S, Zhang Q, Li S, Gao X, Wang J, Jiang L and Liu K (2015). Pten deletion promotes regrowth of corticospinal tract axons 1 year after spinal cord injury. Journal of Neuroscience. 35(26):9754-9763. [Abstract]
4 He J, Xia M, Tsang WH, Chow KL and Xia J (2015). ICA1L forms BAR-domain complexes with PICK1 and is critical for acrosome formation in spermiogenesis. Journal of Cell Science. 128:3822-36. [Abstract]
5 He S, Ye CF, Sun Q, Leung CKS and Qu JY (2015). Label-free nonlinear optical imaging of mouse retina. Biomedical Optics Express. 6(3):1055-1066. [Abstract]
6 Ip FCF, Fu WY, Cheng EYL, Tong EPS, Lok KC, Liang Y, Ye WC and Ip NY (2015). Anemoside A3 enhances cognition through the regulation of synaptic function and neuroprotection. Neuropsychopharmacology. 40(8):1877-87. [Abstract]
7 Jiang H, Sheong FK, Zhu L, Gao X, Bernauer J and Huang X (2015). Markov state models reveal a two-step mechanism of miRNA loading into the human argonaute protein: Selective binding followed by structural re-arrangement. PLoS Computational Biology. 11:e1004404, 1-21. [Abstract]
8 Lai KO and Ip NY (2015). Cdk5: A key player at neuronal synapse with diverse functions. Mini-Reviews in Medicinal Chemistry. 15:1-6. [Abstract]
9 Lai KO, Liang Z, Fei E, Huang H and Ip NY (2015). Cyclin-dependent Kinase 5 (Cdk5)-dependent phosphorylation of p70 ribosomal S6 kinase 1 (S6K) is required for dendritic spine morphogenesis. Journal of Biological Chemistry. 290:14637-46. [Abstract]
10 Li S, He Q, Wang H, Tang X, Ho KW, Gao X, Zhang Q, Shen Y, Cheung A, Wong F, Wong YH, Ip NY, Jiang L, Yung WH and Liu K (2015). Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons. Neurobiology of Disease. 73:366-376. [Abstract]
11 Li X, Lam WJ, Cao Z, Hao Y, Sun Q, He S, Mak HY and Qu JY (2015). Integrated femtosecond stimulated Raman scattering and two-photon fluorescence imaging of subcellular lipid and vesicular structures. Journal of Biomedical Optics. 20(11):110501, 1-4. [Abstract]
12 Li Y, Tong Y and Wong YH (2015). Regulatory functions of Nm23-H2 in tumorigenesis: Insights from biochemical to clinical perspectives. Naunyn-Schmiedeberg's Arch Pharmacology. 388:243-56. [Abstract]
13 Li Y, Zhou H, Li F, Chan SW, Lin Z, Wei Z, Yang Z, Guo F, Lim CJ, Xing W, Shen Y, Hong W, Long J and Zhang M (2015). Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway. Cell Research. 25:801-17. [Abstract]
14 Liang Z, Ye T, Zhou X, Lai KO, Fu AK and Ip NY (2015). Cdk5 regulates activity-dependent gene expression and dendrite development. The Journal of Neuroscience. 35:15127-34. [Abstract]
15 Lu Q, Li J, Ye F and Zhang M (2015). Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling. Nature Structural & Molecular Biology. 22:81-88. [Abstract]
16 Ng YP, Or TC and Ip NY (2015). Plant alkaloids as drug leads for Alzheimer's disease. Neurochemistry International. 89:260-70. [Abstract]
17 Sheong FK, Silva DA, Meng L, Zhao Y and Huang X (2015). Automatic state partitioning for multi-body systems (APM): An efficient algorithm for constructing markov state models to elucidate conformational dynamics of multi-body systems. Journal of Chemical Theory and Computation. 11(1):17-27. [Abstract]
18 Sun Q, Zheng W, Wang J, Luo Y and Qu JY (2015). Mechanism of two-photon excited hemoglobin fluorescence emission. Journal of Biomedical Optics. 20(10):105014,1-6. [Abstract]
19 Tse MK, Morris CJ, Zhang M and Wong YH (2015). Activator of G protein signaling 3 forms a complex with resistance to inhibitors of cholinesterase-8A without promoting nucleotide exchange on Gαi3. Molecular Cellular Biochemistry. 401:27-38. [Abstract]
20 Wei Z, Li Y, Ye F and Zhang M (2015). Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin. Journal of Biological Chemistry. 290:11384-92. [Abstract]
21 Wong WK, Kelly T, Li J, Ma HT and Poon RYC (2015). SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A–B56. Cell Cycle. 14(24):3965-77.[Abstract]
22 Wu W, Wan OW and Chung KK (2015). S-nitrosylation of XIAP at Cys 213 of BIR2 domain impairs XIAP's anti-caspase 3 activity and anti-apoptotic function. Apoptosis. 20:491-9. [Abstract]
23 Xu J, Zhu L, He S, Wu Y, Jin W, Yu T, Qu JY and Wen Z (2015). Temporal-spatial resolution fate mapping reveals distinct origins for embryonic and adult microglia in zebrafish. Developmental Cell. 34(6):632-641 [Abstract]
24 Xu LH, Xie H, Shi ZH, Du LD, Wing YK, Li AM, Ke Y and Yung WH (2015). Critical role of endoplasmic reticulum stress in chronic intermittent hypoxia-induced deficits in synaptic plasticity and long-term memory. Antioxidants and Redox Signaling. 23(9):695-710. [Abstract]
25 Ye T, Fu AK and Ip NY (2015). Emerging roles of Axin in cerebral cortical development. Frontiers in Cellular Neuroscience. 9:217, 1-8. [Abstract]
26 Yoshii A, Constantine-Paton M and Ip NY (2015). Editorial: Cell and molecular signaling, and transport pathways involved in growth factor control of synaptic development and function. Frontiers in Synaptic Neuroscience. 7:8, 1-3. [Abstract]
27 Zhang L, Silva DA, Pardo-Avila F, Wang D and Huang X (2015). Structural model of RNA polymerase II elongation complex with complete transcription bubble reveals NTP entry routes. PLoS Computational Biology. 11:e1004354, 1-21. [Abstract]
28 Zhang P, Fu WY, Fu AK and Ip NY (2015). S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength. Nature Communications. 6:8665, 1-11. [Abstract]
29 Zhao XS, Fu WY, Hung NK, Chien WW, Li Z, Fu AK and Ip NY (2015). NRC-interacting factor directs neurite outgrowth in an activity-dependent manner. Neuroscience. 289:207-213. [Abstract]
2014 top
1 Alam M and He J (2014). Lower-limb neuroprostheses: Restoring walking after spinal cord injury. Emerging Theory and Practice in Neuroprosthetics. 9:153-180. (DOI: 10.4018/978-1-4666-6094-6.ch009), published by IGI-Global. [Abstract]
2 Bi CW, Luk WK, Campanari ML, Liu YH, Xu L, Lau KM, Xu ML, Choi RC, Sáez-Valero J and Tsim KW (2014). Quantification of the transcripts encoding different forms of AChE in various cell types: Real-time PCR coupled with standards in revealing the copy number. Journal of Molecular Neuroscience. 53(3):461-8. [Abstract]
3 Chan KH, Chen YH, Zhang Y, Wong YH and Dun NJ (2014). Angiotensin-[1-12] interacts with angiotensin type I receptors. Neuropharmacology. 81:267-273. [Abstract]
4 Chen J, Maiwulanjiang M, Lam KY, Zhang WL, Zhan JY, Lam CT, Xu SL, Zhu KY, Yao P, Lau DT, Dong TT and Tsim KW (2014). A standardized extract of the fruit of Ziziphus jujuba (Jujube) induces neuronal differentiation of cultured PC12 cells: A signaling mediated by protein kinase A. Journal of Agricultural & Food Chemistry. 62:1890-1897. [Abstract]
5 Chen JP, Yan AL, Lam KY, Lam CT, Li N, Yao P, Xiong AZ, Dong TT and Tsim KW (2014). A chemically standardized extract of Ziziphus jujuba Fruit (Jujube) stimulates expressions of neurotrophic factors and anti-oxidant enzymes in cultured astrocytes. Phytotherapy Research . 28:1727-1730. [Abstract]
6 Chen Y, Ip FCF, Shi L, Zhang Z, Tang H, Ng YP, Ye WC, Fu AK and Ip NY (2014). Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton. The Journal of Neuroscience. 34:2413-242. [Abstract]
7 Choi YK and Qi RZ (2014). Assaying microtubule nucleation by the γ-tubulin ring complex. Methods in Enzymology. 540:119-130. [Abstract]
8 Du CY, Choi RC, Dong TT, Lau DT and Tsim KW (2014). Yu Ping Feng San, an ancient Chinese herbal decoction, regulates the expression of inducible nitric oxide synthase and cyclooxygenase-2 and the activity of intestinal alkaline phosphatase in cultures. PLoS ONE. 9(6):e100382, 1-9. [Abstract]
9 Fang WQ, Chen WW, Jiang L, Liu K, Yung WH, Fu AK and Ip NY (2014). Overproduction of upper-layer neurons in the neocortex leads to autism-like features in mice. Cell Reports. 9:1635-43. [Abstract]
10 Fu AKY, Hung KW, Huang H, Gu S, Shen Y, Cheng EYL, Ip FCF, Huang X, Fu WY and Ip NY (2014). Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease. Proceedings of the National Academy of Science USA. 111(27):9959-9964. [Abstract]
11 Gu S, Silva D-A, Meng L, Yue A and Huang X (2014). Quantitatively characterizing the ligand binding mechanisms of choline binding protein using markov state model analysis. PLoS Computational Biology. 10(8): e1003767, 1-11. (doi:10.1371/journal.pcbi.1003767). [Abstract]
12 Hu J, Lei Y, Wong WK, Liu S, Lee KC, He X, You W, Zhou R, Guo JT, Chen X, Peng X, Sun H, Huang H, Zhao H and Feng B (2014). Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Research. 42(3):1-16. [Abstract]
13 Hu Y, Chan KH, He X, Ho MKC and Wong YH (2014). Synthesis and functional characterization of substituted isoquinolinones as MT2-selective melatoninergic ligands. PLoS ONE. 9: e113638. [Abstract]
14 Ip FC, Ng YP, An HJ, Dai Y, Pang HH, Hu YQ, Chin AC, Harley CB, Wong YH and Ip NY (2015). Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management. Neurosignals. 22:52-63. [Abstract]
15 Ip JP, Fu AKY and Ip NY (2014). CRMP2: Functional roles in neural development and therapeutic potential in neurological diseases. Neuroscientist. 20(6): 589-598. [Abstract]
16 Li Q, Qian ZM, Arbuthnott GW, Ke Y and Yung WH (2014). Cortical effects of deep brain stimulation: Implications for pathogenesis and treatment of Parkinson disease. JAMA Neurology. 71:100-103. (This paper received editorial highlight by the journal). [Abstract]
17 Li X, Yu K, Zhang Z, Sun W, Yang Z, Feng J, Chen X, Liu CH, Wang H, Guo YP and He J (2014). Cholecystokinin from the entorhinal cortex enables neural plasticity in the auditory cortex. Cell Research. 24:307-330. [Abstract]
18 Li Y, Alam M, Guo S, Ting KH and He J (2014). Electronic bypass of spinal lesions: Activation of lower motor neurons directly driver by cortical neural signals. Journal of NeuroEngineering and Rehabilitation. 11:107. [Abstract]
19 Li Y, Wei Z, Yan Y, Wan Q, Du Q and Zhang M (2014). Structure of crumbs tail in complex with PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proceedings of National Academy of Science USA. 111:17444-17449. [Abstract]
20 Li Y, Wei Z, Zhang J, Yang Z and Zhang M (2014). Structural basis of the binding of merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1. Journal of Biological Chemistry. 289(21):14674-14681. [Abstract]
21 Liu P, Choi YK and Qi RZ (2014). NME7 is a functional component of the γ-tubulin ring complex. Molecular Biology of the Cell. 25(13):2017-2025. [Abstract]
22 Ma HT, Erdal S, Huang S and Poon RYC (2014). Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistance. Molecular Oncology. 8:1408-18. [Abstract]
23 Maiwulanjiang M, Chen JP, Xin GZ, Gong AG, Miernisha A, Du CY, Lau KM, Lee PS, Chen JH, Dong TT, Aisa HA and Tsim KW (2014). The volatile oil of Nardostachyos Radix et Rhizoma inhibits the oxidative stress-induced cell injury via reactive oxygen species scavenging and Akt activation in H9c2 cardiomyocyte. Journal of Ethnopharmacology. 153:491-498. [Abstract]
24 Silva D, Weiss D, Pardo-Avila F, Da L, Levitt M, Wang D and Huang X (2014). Millisecond dynamics of RNA polymerase II translocation at atomic resolution. Proceedings of National Academy of Science USA. 111:7665-7670. [Abstract]
25 Tang J, Ip JPK, Ye T, Ng YP, Yung WH, Wu Z, Fang W, Fu AKY and Ip NY (2014). Cdk5-Dependent Mst3 Phosphorylation and activity regulate neuronal migration through RhoA inhibition. Journal of Neuroscience. 34: 7425-7436. [Abstract]
26 Wang C, Wei Z, Chen K, Ye F, Yu C, Bernnet V and Zhang M (2014). Structural basis of diverse membrane target recognitions by Ankyrins. eLife. 3:e04353,1-22. [Abstract]
27 Wang Z, Zhang C and Qi RZ (2014). A newly identified myomegalin isoform functions in Golgi microtubule organization and ER-Golgi transport. Journal of Cell Science. 127:4904-4917. [Abstract]
28 Xin GZ, Hu B, Shi ZQ, Lam YC, Dong TT, Li P, Yao ZP and Tsim KW (2014). Rapid identification of plant materials by wooden-tip electrospray ionization mass spectrometry and a strategy to differentiate the bulbs of Fritillaria. Analytica Chimica ACTA. 820:84-91. [Abstract]
29 Xin GZ, Lam YC, Maiwulanjiang M, Chan GK, Zhu KY, Tang WL, Dong TT, Shi ZQ, Li P and Tsim KW (2014). Authentication of Bulbus fritillariae cirrhosae by RAPD-derived DNA markers. Molecules. 19:3450-3459. [Abstract]
30 Xu J, Kam C, Luo J and Xia J (2014). PICK1 mediates synaptic recruitment of AMPA receptors at neurexin-induced postsynaptic sites. Journal of Neuroscience. 34(46):15415-15424. [Abstract]
31 Yan B, Han P, Pan L, Lu W, Xiong J, Zhang M, Zhang W, Li L and Wen Z (2014). IL-1β and reactive oxygen species differentially regulate neutrophil directional migration and Basal random motility in a zebrafish injury-induced inflammation model. Journal of Immunology. 192:5998-6008. [Abstract]
32 Ye T, Ip JPK, Fu AKY and Ip NY (2014). Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex. Nature Communications. 5(4826):1-14. [Abstract]
33 Zeng Y, Yan B, Sun Q, He S, Jiang J, Wen Z and Qu JY (2014). In vivo micro-vascular imaging and flow cytometry in zebrafish using two-photon excited endogenous fluorescence. Biomedical Optics Express. 5:653-663. [Abstract]
34 Zeng Y, Yan B, Xu J, Sun Q, He S, Jiang J, Wen Z and Qu JY (2014). In vivo nonlinear optical imaging of immune responses: Tissue injury and infection. Biophysical Journal. 107:2436-2443. [Abstract]
35 Zhan JY, Yao P, Bi CW, Zheng KY, Zhang WL, Chen JP, Dong TT, Su ZR and Tsim KW (2014). The sulfur-fumigation reduces chemical composition and biological properties of Angelicae sinensis radix. Phytomedicine. 21:1318-1324. [Abstract]
36 Zhan JY, Zheng KY, Zhang WL, Chen JP, Yao P, Bi CW, Dong TT and Tsim KW (2014). Identification of Angelica oil as a suppressor for the biological properties of Danggui Buxue tang: a Chinese herbal decoction composes of Astragali Radix and Angelica Sinensis Radix. Journal of Ethnopharmacology. 154:825-831. [Abstract]
37 Zhang C, Kho YS, Wang Z, Chiang YT, Ng GKH, Shaw PC, Wang Y and Qi RZ (2014). Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum. PLoS One. 9(1):e85206, 1-11. [Abstract]
38 Zhang L, Silva DA, Yue A, Zhang H, Yan Y and Huang X (2014). Dynamic protein conformations preferentially drive energy transfer along active chain of the photosystem-II reaction center. Nature Communications. 5:4170, 1-9 (doi: 10.1038/ncomms5170). [Abstract]
39 Zhao XS, Fu WY, Chien WWY, Li Z, Fu AKY and Ip NY (2014). p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1). PLoS One. 9(10):e110584 (1-8). [Abstract]
40 Zheng KYZ, Zhang ZX, Du CYQ, Zhang WL, Bi CWC, Choi RCY, Dong TTX and Tsim KW (2014). Ferulic acid enhances the chemical and biological properties of astragali radix: A stimulator for Danggui Buxue Tang, an ancient Chinese herbal decoction. Planta Medica. 80:159-164. [Abstract]
41 Zhu J, Shang Y, Wan Q, Xia Y, Chen J, Du Q and Zhang M (2014). Phosphorylation-dependent interaction between tumor suppressors Dig and Lgl. Cell Research. 24:451-463. [Abstract]
2013 top
1 Cao M, Mao Z, Kam C, Xiao N, Cao X, Shen C, Cheng KKY, Xu A, Lee KM, Jiang L and Xia J (2013). PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance. PLOS Biology. 11:1-13. [Abstract]
2 Chan KH, Cheung AST, Ho MKC and Wong YH (2013). Development of novel melatoninergics as circadian rhythm sleep disorder therapeutics. In: New Developments in Melatonin Research. Ed. Acuna-Castroviejo D, Rusanova I, Escames G. Nova Science Publishers, Inc.. Ch. 4:53-76.
3 Chan KH, Hu Y, Ho MKC and Wong YH (2013). Characterization of substituted phenylpropylamides as highly selective agonists at the melatonin MT2 receptor. Current Medicinal Chemistry. 20(2):289-300. [Abstract]
4 Chan KH and Wong YH (2013). A molecular and chemical perspective in defining melatonin receptor subtype selectivity. International Journal of Molecular Sciences. 14:18385-18406. [Abstract]
5 Chen J, Li Z, Maiwulanjiang M, Zhang WL, Zhan JY, Lam CT, Zhu KY, Yao P, Choi RC, Lau DT, Dong TT and Tsim KW (2013). Chemical and biological assessment of Ziziphus jujuba fruits from China: different geographical sources and developmental stages. Journal of Agricultural & Food Chemistry. 61:7315-7324. [Abstract]
6 Chen J, Li Z, Zheng KY, Guo AJ, Zhu KY, Zhang WL, Zhan JY, Dong TT, Su Z and Tsim KW (2013). Chemical fingerprinting and quantitative analysis of two common Gleditsia sinensis fruits using HPLC-DAD. Acta Pharm. 63:505-515. [Abstract]
7 Chen J and Zhang M (2013). The Par3/Par6/aPKC complex and epithelial cell polarity. Experimental Cell Research. 319:1357-1364. [Abstract]
8 Chen S, Chen J, Shi H, Wei M, Castaneda-Castellanos DR, Bultje RS, Pei X, Kriegstein AR, Zhang M and Shi SH (2013). Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity. Developmental Cell. 24:26-40. [Abstract]
9 Chen X, Guo Y, Feng J, Liao Z, Li X, Wang H, Li X and He J (2013). Encoding and retrieval of artificial visuo-auditory memory traces in auditory cortex needs entorhinal cortex. The Journal of Neuroscience. 33:9963-9974. [Abstract]
10 Chen Y, Fu AK and Ip NY (2013). Axin: An emerging key scaffold at the synapse. IUBMB Life. 65:685-691. [Abstract]
11 Da LT, Avila FP, Wang D and Huang X (2013). A two-state model for the dynamics of the pyrophosphate ion release in bacterial RNA polymerase. PLoS Computational Biology. 9:e1003020. [Abstract]
12 Fang WQ, Chen WW, Fu AKY and Ip NY (2013). Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex. Neuron. 79:665-679. [Selected by Neuron to be accompanied with a video abstract. The video is featured on the Neuron website (; and is accessible in YouTube channel ( hD9P_ FUc)]  [Abstract]
13 Hu Y, Zhu J, Chan KH and Wong YH (2013). Development of substituted N-[3-(3-methoxylphenyl)propy1] amides as MT2-selective melatonin agonists: improving metabolic stability. Bioorganic & Medicinal Chemistry. 21:547-552. [Abstract]
14 Jia J, Fong KW, Choi YK, See SS and Qi RZ (2013). Dynamic recruitment of CDK5RAP2 to centrosomes requires its association with dynein. PLoS One. 8:e68523. [Abstract]
15 Lai KO and Ip NY (2013). Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders. Biochimica et Biophysica Acta. 1832:2257-2263. [Abstract]
16 Lau WWI, Chan ASL, Poon LSW, Zhu J and Wong YH (2013). Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms. Cell Communication and Signaling. 11:22. [Abstract]
17 Li X, Mao Z, Wu M and Xia J (2013). Rescuing infertility of Pick1 knockout mice by generating testis-specific transgenic mice via testicular infection. Scientific Reports. 3:2842. [Abstract]
18 Maiwulanjiang M, Zhu KY, Chen J, Miernisha A, Xu SL, Du CY, Lau KK, Choi RC, Dong TT, Aisa HA and Tsim KW (2013). Song bu li decoction, a traditional uyghur medicine, protects cell death by regulation of oxidative stress and differentiation in cultured PC12 cells. Evidence-based Complementary and Alternative Medicine. 2013:687958. [Abstract]
19 Ng YP, Chen YW, Hu YQ, Ip FCF and Ip NY (2013). Olean-12-eno[2,3-c][1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines. PLoS One. 8:e63580. [Abstract]
20 Pan Z, Zhu J, Shang Y, Wei Z, Jia M, Xia C, Wen W, Wang W and Zhang M (2013). An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs. Structure. 21:1007-017. [Abstract]
21 Qiao Q, Bowman GR and Huang X (2013). Dynamics of an intrinsically disordered protein reveal metastable conformations that potentially seed aggregation. Journal of the American Chemical Society. 135(43):16092. [Abstract]
22 Shen Y, Fu WY, Cheng EYL, Fu AKY and Ip NY (2013). Melanocortin-4 receptor regulates hippocampal synaptic plasticity through PKA-dependent mechanism. The Journal of Neuroscience. 33(2):464-472. [Abstract]
23 Sun Q, Li Y, He S, Situ C, Wu ZG and Qu JY (2013). Label-free multimodal nonlinear optical microscopy reveals fundamentals insights of skeletal muscle development. Biomedical Optics Express. 5(1):158-166. [Abstract]
24 Tsang WH, Wang B, Wong WK, Shi S, Chen X, He X, Gu S, Hu J, Wang C, Liu PC, Lu G, Chen X, Zhao H, Poon WS, Chan WY and Feng B (2013). LIF-dependent primitive neural stem cells derived from mouse ES cells represent a reversible stage of neural commitment. Stem Cell Research. 11:1091-1102. [Abstract]
25 Tso PH, Wang Y, Yung LY, Tong Y, Lee MMK and Wong YH (2013). RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras. Cellular Signalling. 25:1064-1074. [Abstract]
26 Wang L, Wang L, Huang W, Su H, Xue Y, Su Z, Liao B, Wang H, Bao X, Qin D, He J, Wu W, So KF, Pan G and Pei D (2013). Generation of integration-free neural progenitor cells from cells in human urine. Nature Methods. 10:84-89. [Abstract]
27 Wang Y, Tong Y, Tso PH and Wong YH (2013). Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis. Cancer Letters. 339:33-41. [Abstract]
28 Wei Z, Liu X, Yu C and Zhang M (2013). Structural basis of cargo recognitions for class V myosins. Proceedings of the National Academy of Science USA. 110:11314-11319. [Abstract]
29 Wong CCK and Wong YH (2013). High-throughput screening in traditional Chinese medicine-based drug discovery. In: Antitumor Potential and Other Emerging Medicinal Properties of Natural Compounds (Fang EF and Ng TB eds). 26:387-403. Springer Publisher. [Abstract]
30 Xu SL, Zhu KY, Bi CWC, Choi RCY, Miernisha A, Yan AL, Maiwulanjiang M, Men SWX, Dong TTX and Tsim KW (2013). Flavonoids induce the expression of synaptic proteins, synaptotagmin and post-synaptic density protein-95, in cultured rat cortical neurons. Planta Med. 79(18):1710-1714. [Abstract]
31 Xu SL, Zhu KY, Bi CW, Yan L, Men SW, Dong TT and Tsim KW (2013). Flavonoids, derived from traditional Chinese medicines, show roles in the differentiation of neurons: possible targets in developing health food products. Birth Defects Research (Part C) Embryo Today. 99:292-299. [Abstract]
32 Ye F and Zhang M (2013). Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures. Biochemical Journal. 455(1):1-14. [Abstract]
33 Zeng Y, Yan B, Sun Q, He S, Jiang J, Wen Z and Qu JY (2013). In vivo micro-vascular imaging and flow cytometry in zebrafish using two-photon excited endogenous fluorescence. Biomedical Optics Express. 5(3):653-663. [Abstract]
34 Zeng Y, Yan B, Sun Q, Teh SK, Zhang W, Wen Z and Qu JY (2013). Label-free in vivo imaging of human leukocytes using two-photon excited endogenous fluorescence. Journal of Biomedical Optics. 18(4):040504. [Abstract]
35 Zhang Y, Wang W, Chen J, Zhang K, Gao F, Gao B, Zhang S, Dong M, Besenbacher F, Gong W, Zhang M, Sun F and Feng W (2013). Structural insights into the intrinsic self-assembly of par-3 N-terminal domain. Structure. 21:997-1006. [Abstract]
36 Zhu KY, Xu SL, Choi RC, Yan AL, Dong TT and Tsim KW (2013). Kai-xin-san, a chinese herbal decoction containing ginseng radix et rhizoma, polygalae radix, acori tatarinowii rhizoma, and poria, stimulates the expression and secretion of neurotrophic factors in cultured astrocytes. Evidence-based Complement Alternative Medicine. 731385:1-9. [Abstract]
37 Zuo H, Chan ASL, Ammer H and Wong YH (2013). Activation of Gαq subunits up-regulates the expression of the tumor suppressor Fhit. Cellular Signaling. 25:2440-2452. [Abstract]
38 Zuo H, Chan GPW, Zhu J, Yeung WWS, Chan ASL, Ammer H and Wong YH (2013). Activation state-dependent interaction between Gαq subunits and the Fhit tumor suppressor. Cell Communication & Signaling. 11:59. [Abstract]
2012 top
1 Jia M, Li J, Zhu J, Wen W, Zhang M and Wang W (2012). Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi. Journal of Biological Chemistry. 287:36766-36776. [Abstract]
2 Li Q, Ke Y, Chan DC, Qian ZM, Yung KK, Ko H, Arbuthnott GW, Yung WH (2012). Therapeutic deep brain stimulation in Parkinsonian rats directly influences motor cortex. Neuron. 76:1030-41. [Abstract]
3 Wang C, Shang Y, Yu J and Zhang M (2012). Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCι in complex with a substrate peptide from Par-3. Structure. 20:791-801. [Abstract]
4 Zhu J, Shang Y, Chen J and Zhang M (2012). Structure and function of the guanylate kinase-like domain of the MAGUK family scaffold proteins. Frontiers in Biology. 7:379-396. [Abstract]